At Ribocure, we are driven by science and innovation, with a mission to establish a world-leading company in RNA research and development, ultimately making a positive impact on patients worldwide.

The Role: Clinical Bioanalytical Scientist

Our clinical portfolio is growing, with our key siRNA assets advancing to later stages of clinical development, and with innovative approaches, such as extra-hepatic siRNA assets, advancing toward clinical phases. We are now looking for a Clinical Bioanalytical Scientist/Expert to support our Clinical Programs and our Clinical Sample Management Team with bioanalytical expertise throughout our clinical development programs.

This role will be part of the Clinical Pharmacology, Statistics & DMPK function. You will collaborate closely with roles across our organization, in a dynamic and pragmatic, fast-paced biotech setting. The role will be a supportive scientific bioanalytical expertise role to the Sample Management Lead (SML) in Clinical Operations, who oversees method development and validation, analytical activities at CROs, and all aspects of sample management in our clinical trials. The successful candidate for this role, will provide expert technical oversight and scientific support for clinical bioanalytical activities, to facilitate internal decision making and regulatory compliance.

Priority will be given to candidates living in proximity to our Göteborg office in the vibrant GoCo area, to allow the majority of the work to be conducted on site. However, for the right candidate, we may also consider partly remote solutions, although with significant time spent at the Göteborg office on a regular basis.

Key Responsibilities

This role will collaborate closely with the Sample Management Lead (SML), the Clinical Pharmacology Lead, the Medical Director and other members of the clinical project teams, as well as with preclinical bioanalytical expertise for method transfer to the clinical setting. You will be responsible for ensuring the scientific quality and technical feasibility of clinical bioanalytical activities. The role will provide technical expertise in selection of appropriate clinical analytical assays, method development, validation, sample analysis and documentation, fulfilling regulatory expectations, across our clinical portfolio. Strong, solid hands-on experience with such tasks in relation to clinical PK and ADA bioanalysis is required, and depending on the background and experience of the candidate, the role may also support with method identification, development, validation, sample analysis and documentation to regulatory standards, of other clinically related analytes, such as pharmacodynamic (PD) biomarkers.

No wet-work is currently expected in this role, but strong laboratory hands-on experience in bioanalytical methodologies relevant to clinical siRNAs and/or other oligonucleotide ‑based therapeutics is key for being successful in this role.

An important part of the role is supporting the SML as required with expert input in contacts with clinical bioanalytical vendors, such as evaluation of CRO bioanalytical technical capabilities, communication and troubleshooting with CROs during method development, validation and sample analysis, and review and approval of analysis plans and reports. Ideally, and depending on the experience of the candidate, the role may also support the SML and the clinical teams with bioanalytical related regulatory interactions. Some operational support in sample management handling together with the SML, is also expected, in line with our “biotech hands-on, can-do” culture.

Close collaboration with the preclinical bioanalytical and translational teams, based at Suzhou Ribo Life Science Co., Ltd. in China, will be key for ensuring efficient transfer of preclinical bioanalytical expertise to the clinical setting.

Required Skills and Experience:

- Solid (eg 5+ years) previous hands-on experience in oligonucleotide relevant bioanalytical methodologies (including but not limited to LC-MS) relevant to clinical plasma and urine PK as well as ADA assessment

- Adequate experience of working with bioanalysis of oligonucleotides in biological matrices, and if not yet an expert in the siRNA bioanalysis field – a strong interest and strong potential for becoming an expert in a reasonable time frame

- Solid, previous hands-on experience in successfully contributing to identification, development and validation of clinical PK and ADA methodologies in relation to clinical trials

- Solid, previous hands-on experience in documentation fulfilling regulatory standards in relation to clinical bioanalysis, such as:

o Technical review and approval of PK and ADA method development and validation protocols

o Review and approval of PK and ADA method validation (and potential cross-validation) reports

o Review of sample analysis data and bioanalytical reports

- Adequate understanding of pharmacokinetics and immunogenicity assessments in a clinical setting

- Solid experience and strong understanding of the clinical drug development process in a pharma industry or biotech setting, and how to ensure that bioanalytical activities are aligned with clinical development plans, clinical trial objectives and strategies

- Track-record in successful efficient cross-functional collaboration in a pharma industry or biotech setting, as well as with external partners, including with bioanalytical vendors in an international setting

- Strong written and verbal English. Strong communication skills and experience in working across different geographies and cultures

- Working style that thrives in an innovative, fast-paced entrepreneurial setting, with willingness to take on responsibility and demonstrating both strong collaboration skills, and the capacity for independent, self‑directed work

Desirable Skills and Experience:

- Experience in clinical bioanalysis of additional analytes, eg PD biomarkers

- Adequate understanding of how PKPD and Model Informed Drug Development can inform Clinical development programs

- Experience in regulatory interactions across the clinical development program, including late phase (Ph2b, Ph3 and submissions)

- Experience with biobanking, including sample collection, long‑term storage, and compliance with ethical and regulatory requirements across multiple countries, including country‑specific informed consent practices.

Why Join Us?

We offer more than a job – we offer a mission. You’ll be part of a tight-knit, friendly team working on real challenges with real potential. Your ideas matter. Your work matters. And your growth matters to us.

Ready to Apply?

We encourage you to submit your CV and cover letter promptly, as applications will be reviewed on an ongoing basis. Final application deadline: May 31, 2026

Hiring manager: Lotta (Ann-Charlotte) Egnell , Global Head of Clinical Pharmacology, Statistics and DMPK